KT: Type of Kinetics

Type of kinetics is an attribute that describes the kind of rate law (RL) as observed experimentally or derived analytically from the reaction mechanism (ME). This attribute is always set by the staff to one or a combination of the following codes:

-BP or -BPH biphase decrease
-EXP exponential decrease
-L linear decrease
-NL non-linear decrease
-S sigmoidal decrease
-STF step-function decrease
O zero level
BP or BPH biphase increase
DEC decrease
H hyperbolic increase
-H hyperbolic decrease
HO harmonic oscillations
DO damped oscillations
OSC oscillations
UDO undamped oscillations
IL intersecting line
INC undefined type of increase
L linear increase
LAG lag
MAX a maximum
MIN a minimum
N negative cooperativity
NL non-linear increase of unidentified type
PL plateau
S sigmoidal increase
SI substrate inhibition
STF step-function increase
H hyperbolic

Example:

SU KM KT VM MA KC CEF
estrone 0.015 H; S; MAX; MIN; MAX; MIN; MAX 0.0125 0.935 0.935 6.23e4

In this example, KT is used to characterise a complicated dependence of the reaction rate on the concentration of the substrate, estrone:

hyperbilically rising curve with inflection point and oscillations

This dependence is apparently hyperbolic at low concentrations (H), then changes to a sigmoidal increase (S) followed by three maxima (MAX) and two minima (MIN).